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Topwine

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  1. Ketones in your urine is excess that is not utilised by your body. That mean your body makes more ketones that it is able to, or want to, use. Maybe you need more than 100 grams of carbs to avoid ketosis for your activity level ?
  2. Ketogenic diet and cancer Thomas Seyfried, PhD is widely regarded as one of the leaders in the world in the research field of ketogenic diets and cancer. Below is a link to a very recent interview where he shares some of his current views. Some interesting points to remember. http://www.townsendletter.com/Jan2014/warburg0114.html The current view now, without any question, is that cancer is a genetic disease. If you go on the National Cancer Institute website or you read any of the major articles published in Nature and Science, often the articles will start with, "Cancer is a genetic disease." I think that this has become dogma. It turns out that the oncogenes are responding to the abnormal metabolism of the cell and we were able to show this. It is actually the abnormal metabolism of the cell that's dictating the genetic mutations. This is where my book challenges the field. It provides credible scientific evidence that seriously questions the notion that cancer is a genetic disease. And I think you are not going to make major advances in the field of cancer until this becomes more widely recognized. We gave animals unrestricted ketogenic diets and the tumor cells grew just as fast, or even faster sometimes, than a standard high-carbohydrate diet. So we said, what's going on here? There's a diet with zero carbohydrate and the animals are eating as much as they want and when we looked at their blood, their blood sugars were very high. So it turns out if you eat large amounts of fat in a ketogenic diet you get insulin insensitivity, which then increases the level of sugar, and the cancer cells are fat and happy using this. So you have to restrict the diet. There are some people out there, like any media thing, they'll say, "Oh, the ketogenic diet cures cancer." We know there's no evidence for that. We haven't used it long enough to know if anybody is going to be cured from cancer using a ketogenic diet. All we can say is that the ketogenic diet has the potential to arrest the growth of the tumor.
  3. I think one must also keep in mind that a lot (most ?), of the weight loss the first few weeks, is water with the associated glycogen stores. That can also account for a lot more sweating and/or peeing in the beginning of a HFLC diet.
  4. Same principle at play here I would think. Don't know why some would sweat it out more rather than pee it out. Will have to research that, but I would guess that maybe you would rather sweat it out if you need more cooling, ie have a high body temperature or metabolic rate. Interesting to note that a camel can theoretically "produce" up to 1.4 Litres of water for every 1 kg of fat stored in it's hump ...
  5. When I was on LCHF, I experienced the same. A lot more perspiration than normal. After studying the chemical formulas, I think I know now why. For the same reason as that you require more oxygen for the same energy output while burning more fat than glucose, you will also form more water ( H2O ) as waste product with the O2 combining with the extra H2 molecules in fat compared to glucose.
  6. I have said it before, and I'll say it again. Peter Attia is wrong. He probably flunked his chemistry class. You ALWAYS need glucose, not just "sometimes". Also, burning fat IS NOT more efficient than burning glucose ! Why are these points even brought up again ? Everyone here is saying how they need extra glucose intake for higher intensity exercise. The chemistry predicts it, and people's experience just confirms it. EOS
  7. Tim Noakes just tweeted this article as a balanced view on LCHF diets for cyclists. I tend to agree. http://cyclingtips.com.au/2013/09/high-fat-low-carb-diets-the-effects-and-how-to-try-one/
  8. Funny, how suddenly there is a thyroid disclaimer in. Maybe Tim Noakes is reading this forum ... The amount of hyperbole re sugar is poisonous , alcohol is toxic, etc, etc is overwhelming, but in the end they leave alcohol consumption up to oneself, but carbs not ? And no mention of PUFA's ? They also call this a Banting diet, but William Banting ate bread, and his diet certainly was not zero carb. http://carbsanity.blogspot.com/2013/10/the-real-diet-of-william-banting-that.html Interestingly he didn't eliminate bread entirely. He had up to 4 slices a day. He lived to be 81 for what it's worth. Why now? Well this letter was cited yet again in a recent "study" by Taubesian newcomer Tim Noakes, that was miraculously published in the South African Medical Journal. I plan on blogging about that shortly and figured this made for a post on its own.
  9. Mark Sisson is no Ray Peat, and a master of spin, but I'll admit he got it right on most, (not all), counts. The study he cites in "support" for Omega 3 oils as "increasing thyroid function", is however why I will rather trust the advice and interpretation of Ray Peat's experience vs Mark Sisson's. The only thing that study points out is that compared to Omega 6 oils, the thyroid "receptor" activity is increased. So not compared to people eating a diet deficient, or at least limited, in PUFA's and certainly they did not compare effects of normal good thyroid function vs on a PUFA diet. Here is a good recent review study highlighting the role of thyroid hormone in hepatic (liver) lipid metabolism. http://joe.endocrinology-journals.org/content/216/3/R47.long Thyroid hormones are important modulators of lipid metabolism because the liver is a primary hormonal target. The liver is the major site for cholesterol and triglyceride metabolism, and thyroid hormones play an important role in hepatic lipid homoeostasis (Malik & Hodgson 2002). Cholesterol is an essential constituent of most biological membranes and it is also a precursor in the synthesis of bile acids, steroid hormones and some vitamins. Normal serum thyroid hormones levels are essential for the maintenance of a sufficient pool of cholesterol to meet the body's requirements and to regulate the critical steps of cholesterol synthesis, uptake and metabolism Long story short, if your bloodwork shows impaired lipid profiles, suspect a liver not functioning properly, or thyroid hormone function(at gland and/or cell level), or both .
  10. I agree. Cholesterol is a protective adaption mechanism. Ray Peat and Tim Noakes is in agreement on cholesterol and statins. For a great article on cholesterol, read this, http://raypeat.com/articles/articles/cholesterol-longevity.shtml
  11. http://ajcn.nutrition.org/content/91/3/578.long Lack of suppression of circulating free fatty acids and hypercholesterolemia during weight loss on a high-fat, low-carbohydrate diet Conclusions In conclusion, our data indicate that a high-fat diet, instead of a calorie- and fat-restricted diet, increased LDL-cholesterol concentrations over 6 wk, and that this effect related at least in part to the lack of suppression of both fasting FFA and FFA measured hourly for 24 h. Despite this adverse effect, weight loss was not greater in the High Fat group. Thus, these data suggest that a high-fat diet may have adverse metabolic effects during active weight loss. note : In fact, there was a 2-fold increase in 24-h FFA within the High Fat group between baseline and 6 wk (mean ± SD high-fat change: 4486 ± 2293 μmol/L; P < 0.0001) and a significant difference in 24-h FFA between groups (mean ± SD high-carbohydrate 24-h FFA compared with high-fat 24-h FFA: 4798 ± 1373 compared with 9686 ± 1801 μmol/L, respectively; P < 0.0001) So what does this mean? It means a HFLC diet liberates a lot more free fatty acids than a higher carb diet in your blood. If you are eating PUFA's, or have been eating them your whole life, these PUFA FFA are preferentially liberated and they are highly oxidising causing a multitude of metabolic problems over time. FFA also cause insulin resistance and increased blood glucose.
  12. No , just repackaged and remarketed in new social media mass market. Ala Tim Noakes diet. Helps to sell a lot of books too.
  13. It's you who should pay attention. The Q&A was about those that was suspended, not warned.
  14. "my view" on moderation of thehub has not been put to the test of independent opinion afaik. "my view" is also shared by others. not everyone shares their view publicly. It's like complaints of bad company service or products. But in your opinion, being popular and in the majority equals being right. If I were to follow that philosophy in the financial markets, I'd have to buy all the popular shares at inflated prices and never make money, or I'd have to argue Zuma is always right.
  15. I am not missing the point. You are suggesting the "populist" opinion should rule and minority opinion oppressed.
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