The simple answer to this question is very easy. Check the data, both cox1 and cox2 inhibitors are not a good idea for endurance event or training. The risk of gromerular nephitis (kidney failure high). That is why if you check in any medical tent at any endurance event, (IM.70.3)These drugs are outlawed. My advise stay away, unless you have a identical twin is willing to donate you a kidney.