You have my sympathies too ! I got Glandular Fever just before my 18th birthday (they don't call it the kissing disease for nothing !) and it flattened me like the person above, sleeping 16 hours a day, totally wiped out. I recovered after about 2 months and then went and did a long cycle, 24 hours later it was back and I was flattened for another month. It almost ruined my exams at that stage of my life. I then went to varsity with it a thing of the past (no symptoms in previous 4 months), joined the university hockey team, trained my guts out and got flattended again with it. My neck glands also swelled up and I could feel that lethargic feeling just radiating out of my neck all the time. Keeping off alcohol I have come to realise is important and, then drink loads of water everyday, it really helped bring the symptoms down for me if I put a pint mug next me when I work and constantly sip & refill. Put up with more frequent toilet trips, its worth it. I also found that I felt worst when I drank hot liquids (tea / coffee / soup etc) and so I stopped all that as well when I had symptoms. You'll have to find out what works for you. So any advice around taking a COMPLETE BREAK I would go with. I am one of the few people though that got it recurring for life, very few people I speak to ever had a recurrence but I have been flattened a number of times in my life and I am now 47. What I found was that if I did huge amounts of exercise (really tiring myself out) and I did it with a cold or virus in my system and, worst still, when the weather was really cold, that I could get the symptoms back again. Not as bad as when I first had it but never the less it screwed up the next 2-3 months. Over the years I have asked every doctor I've ever visited as my GP for advice and they always seem surprised that it re-occurs, having little idea on how to handle. A possible break through came for me when I described the above pattern to my current GP who said that if exercising when a cold / virus is happening or has just happened in the recent past is a reason why symptoms can kick off (irrespective of whether I cycled) then I should work to improve my immune system. His advice which I have now followed for the past 4 years was to have an 'intragam' injection at the start of each winter (during April) .. he uses it and hasn't been ill for 20 years, all his nurses / nursing sisters use it too and claim great success with reduced illness levels. Plenty on the web about it. Since starting it I have hardly been ill and sore throats that appear usually disappear in a day or so, completely different to my previous experience of going down every 3-4 months with something nasty. So I suppose I just had a crappy immune system from day 1. I am now doing more exercise than I have ever done in my life, riding long MTB rides (up to 100-120km) and having an absolute ball. I still listen to my body though ... if I get a cold starting up, my glands can react pretty quick, so I back off until the glands go down, these days that's about 2 days instead of my previous 2-3 months experience. As I said, you have my sympathies ... statistically though you should not have my experience of best part of 30 years having it recur ! If it does recur, perhaps chat to your GP about the Intragam injection. Take it easy, T.